SERCA2a upregulation ameliorates cellular alternans induced by metabolic inhibition
نویسندگان
چکیده
منابع مشابه
SERCA2a upregulation ameliorates cellular alternans induced by metabolic inhibition.
Cardiac alternans has been associated with the incidence of ventricular tachyarrhythmias and sudden cardiac death. The aim of this study was to investigate the effect of impaired mitochondrial function in the genesis of cellular alternans and to examine whether modulating the sarcoplasmic reticulum (SR) Ca(2+)ameliorates the level of alternans. Cardiomyocytes isolated from control and doxycylin...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2016
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.00588.2015